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CARBAFORM

A simple platform for tunable antibody fucosylation

About

Anticancer antibodies primarily act through a mechanism called antibody-dependent cell-mediated cytotoxicity (ADCC). Decreasing antibody fucosylation enables up to 50-fold improvement in ADCC activity - with the added benefit of allowing targeting of low-density antigens. 

At Carbaform Biosciences we have developed a convenient feed additive that allows producing antibodies with tunable levels of fucosylation. Simple to use with existing cell lines without affecting cell growth or antibody titer.

Carbaform is seeking to partner its technology to help accelerate the delivery of life-saving new therapeutics and biobetters. Click below to find out more about our technology and tools. 

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