
CARBAFORM
A simple platform for tunable antibody fucosylation
About
Anticancer antibodies primarily act through a mechanism called antibody-dependent cell-mediated cytotoxicity (ADCC). Decreasing antibody fucosylation enables up to 50-fold improvement in ADCC activity - with the added benefit of allowing targeting of low-density antigens.
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At Carbaform Biosciences we have developed a convenient feed additive that allows producing antibodies with tunable levels of fucosylation. Simple to use with existing cell lines without affecting cell growth or antibody titer.
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Carbaform is seeking to partner its technology to help accelerate the delivery of life-saving new therapeutics and biobetters. Click below to find out more about our technology and tools.
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